Best Cheap Dog Heartworm Prevention Options and Value Guide
For affordable heartworm prevention, compare the dog’s correct weight range, monthly supply, and whether you need protection for fleas, ticks, or intestinal worms too. HEARTGARD Plus is a focused heartworm-prevention option; NexGard Plus and Simparica Trio combine heartworm prevention with other parasite protection, while Credelio Quattro lists broad coverage. PetArmor 7-Way is a dewormer, not a heartworm preventive, so it is not a substitute. A veterinarian can help choose a safe product and advise about heartworm testing.
| Product | Best suited for | Key distinction |
|---|---|---|
| HEARTGARD Plus | Dogs needing a focused monthly preventive | Also controls roundworms and hookworms |
| NexGard Plus | Dogs needing combined parasite protection | Heartworm preventive with flea and tick protection |
| Simparica Trio | Dogs needing a combination chew | Monthly chew for the listed 22.1–44 lb range |
| Credelio Quattro | Small dogs needing broad listed coverage | Seven parasite types listed |
| PetArmor 7-Way | Dogs needing worm treatment | Not a heartworm preventive |
HEARTGARD Plus Chews

Best for: Owners looking for a focused heartworm preventive for a dog up to 25 pounds. The listing describes HEARTGARD Plus as a veterinarian-recommended preventive that also treats and controls roundworms and hookworms. Its real-beef chew format may suit owners seeking a chew rather than another form of medication.
Choose this if heartworm prevention and the listed intestinal-worm coverage fit your needs. The supplied listing identifies a one-month supply, so continued prevention requires planning for regular refills. It does not list flea or tick protection; choose a separate product if your veterinarian recommends that coverage.
NexGard Plus For Small Dogs

Best for: Dogs weighing 8.1–17 pounds whose owners want heartworm prevention combined with flea and tick protection. The listed chew contains afoxolaner, moxidectin, and pyrantel, and is presented as a one-month supply with a beef flavor.
Choose this if a combined chew better matches your dog’s parasite-prevention plan than a heartworm-only product. The main limitation is its specific weight range: the listed size is not for dogs outside 8.1–17 pounds. Confirm the correct dose with a veterinarian rather than splitting or substituting a size.
Simparica Trio Chewable

Best for: Owners of dogs weighing 22.1–44 pounds who are considering a monthly combination chew. The product listing identifies it as Simparica Trio and gives the flavor, weight range, and one-month supply; the product name also identifies sarolaner and moxidectin.
It may be a better fit than a small-dog package when the dog falls within this listed range. The supplied product details do not specify the full parasite coverage, so check the current label and ask a veterinarian what protection it provides before comparing it with products that list coverage explicitly.
Credelio Quattro For Small Dogs

Best for: Dogs weighing 6.1–12 pounds whose owners want a chew with several parasite targets listed. The product information describes seven-way coverage, including heartworm disease, fleas, ticks, New World screwworm larvae, roundworms, hookworms, and tapeworms. It also states that the chew begins killing certain listed fleas and ticks within four hours.
Choose this if the listed broad coverage aligns with your veterinarian’s plan. The package is a one-count listing, and its weight range is narrow. Read the applicable label carefully; the supplied description includes specific tick species and claims, not a guarantee that every parasite is covered in every circumstance.
Buying Guide: How To Compare Dog Heartworm Prevention
Should you choose a heartworm-only or combination product?
A focused preventive such as HEARTGARD Plus may suit owners who need heartworm prevention and the additional worm coverage listed for that product. Combination chews can be more convenient when flea, tick, or other parasite protection is also needed. Compare the exact label coverage rather than assuming all combination products protect against the same parasites.
How can you find the lowest overall cost?
Compare the cost per month for the correct weight range, not just the package total. Account for how many monthly doses are included and whether the product replaces other treatments your veterinarian recommends. The listed items vary in package size, so a one-chew listing should not be compared directly with a multi-month supply without calculating the same time period.
Why does weight range matter?
Each listing specifies a dog weight range, and the products shown do not all fit the same dogs. Weigh your dog and confirm the correct product strength with a veterinarian. Do not use a package outside its stated range or divide a chew unless a veterinarian directs you to do so.
Is a dewormer the same as heartworm prevention?
No. PetArmor 7-Way treats and controls specified intestinal worms, but its listed features do not include heartworm prevention. It should not be used as a replacement for a heartworm preventive. Ask a veterinarian which product addresses each parasite risk.
Frequently Asked Questions
What is the cheapest way to prevent heartworm in a dog?
Compare the per-month cost of products prescribed for your dog’s weight and needs. The least expensive package may not be the best value if it does not provide the coverage your veterinarian recommends.
Can I buy dog heartworm prevention without asking a veterinarian?
Ask a veterinarian before starting or changing prevention. They can advise whether testing is appropriate and help select a product and dose for your dog.
Does PetArmor 7-Way prevent heartworm?
No. Its listed uses cover seven types of intestinal worms; heartworm prevention is not among the supplied product features.
Do combination chews replace every parasite treatment?
Not necessarily. Coverage differs by product. Check the current product label and confirm with a veterinarian which parasites are included in your dog’s prevention plan.